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Identification and Analysis of the Role of Chitinase Substrate in Francisella Novicida

Besse, Katherine

Francisella tularensis is a gram negative facultative intracellular pathogen which is a class A biothreat according to the CDC. This bacteria codes for two chitinases (ChiA and ChiB) and one chitin binding protein (CbpA). ...
Identification and Prediction of Intrinsically Disordered Regions in Proteins

Mauricio Oberti (2019)

It has been the dominant paradigm in structural biology that a well-defined structure determines protein function. Intrinsically disordered proteins (IDPs), which lack a stable three-dimensional structure under ...
Identification of a CBF-β RUNX1 Inhibitor Which Blocks HIV-1 Infection

Goad, Taylor (2015-10-23)

Human Immunodeficiency Virus (HIV) is a single-stranded RNA retrovirus and the causative agent of Acquired Immunodeficiency Syndrome (AIDS). Established antiretroviral therapy (ART) is mostly efficient in reducing viral ...
Identification of Modulators of HIV-1 and HTLV-1 Mediated Proviral Transcription from a Library of FDA Approved Pharmaceuticals

Sampey, Gavin Charles (2015)

Human immunodeficiency virus 1 (HIV-1) and human T-lymphotropic virus 1 (HTLV-1) comprise the two most prevalent human retroviruses. Recent epidemiological data shows that 34 million people are living with HIV-1 worldwide, ...
IDENTIFICATION OF NOVEL EPIGENETIC BIOMARKERS FOR EARLY DETECTION IN VARIOUS CANCER TYPES

GOUD, SANTOSH MAHADEVANA (2017)

Abstract
Identification Of Novel Epigenetic Biomarkers For Early Detection In Various Cancer Types

Goud, Santosh Mahadevana (George Mason University, 2017)

Epigenetic landscape of cancer cells undergoes profound and signicant changes duringthe development of human malignancies. In fact, global changes in the epigenetic landscapeare a hallmark of cancer. Histone modications ...
Identification of Potential Tuberculosis Biomarkers Using Combination of Nanotrap Particles and Mass Spectrometry

Hunter, Monique E (2015-10-23)

Mycobacterium tuberculosis (MTB), the etiological agent of tuberculosis, is still a major public health problem despite the tremendous effort to eradicate it. The unique dynamism between the host and the bacilli leads ...
Identification Of PSGLl-1 And The SHREK Family Of Proteins As Broad-Spectrum Antiviral Host Factors

Deemah Dabbagh (2021)

PSGL-1 (P-selectin glycoprotein ligand-1) is a dimeric, mucin-like glycoprotein with a molecular weight of 120 kDa and functions as a ligand for P-, E-, and L-selectins. PSGL-1 is predominantly expressed on the surface of ...
Identification, Quantification and Distribution of Polychlorinated Biphenyls (PCBs) in Sediments of the Rappahannock and York River Watersheds

Cooper, Budoin-Brutus (2012-10-05)

This study is intended to contribute to an understanding of water quality in a portion of the Chesapeake Bay: the Rappahannock and York watersheds. My PhD dissertation research is to identify, quantify, and determine the ...
Identifying and Projecting Novel Long-Term Phenological Trends: Integrating Heterogeneous Data Sources

Garretson, Alexis

Studies of climate change in deciduous forest communities mainly document the earlier appearance of spring leaves and later senescence in autumn. However, climate change can create novel patterns of growth or shift other ...
Identifying chemical signals and examining their role in reproduction in the maned wolf (Chrysocyon brachyurus)

Jones, Marieke Kester (2017)

The maned wolf (Chrysocyon brachyurus) is a Neotropical canid species that exhibits a rare reproductive mechanism, induced ovulation. Unlike most other canids, the maned wolf is solitary, so induced ovulation is an important ...
Identifying the Relationship between the Gut Microbiome and Inflammatory Bowel Disease in the Captive Red Wolf (Canis rufus)

Bragg, Morgan

Captive management of many wildlife species has proven to be challenging, with individuals displaying health disorders that are not generally described in the wild population. Retrospective studies have identified ...
Identifying, Extracting, and Georeferencing Toponyms from a Nineteenth-Century Text

Dorman, Eric

This thesis explores the process of recreating and mapping a journey from an 1863 work of realistic fiction, Five Weeks in a Balloon, by Jules Verne. As with many of Verne’s works, the novel is a geographically-rich story ...
IMAGE ANALYSIS OF RADIOLOGICAL IMAGES FROM PATIENTS WITH ADVANCED LUNG DISEASE

Acharya, Mekhala (2012)

There are diagnostic challenges in the evaluation of a patient with a known or suspected diagnosis of interstitial lung disease [ILD] because of the extensive possibilities of diverse potential diagnoses with similar ...
IMMERSIVE DEEP MAPS FOR ARCHAEOLOGICAL SITES: PRESENCE AND PLACE ACROSS TIME AND SPACE THROUGH VIRTUAL REALITY

Alisa Pettitt (2021)

Presenting complex spatiotemporal environmental and cultural archaeological site information in traditional museum exhibits is a challenge. The site data exists, meticulously documented in modern archaeological mapping ...
Impact of Climate on Eastern U.S. Wine Production

MacCracken, Rosalyn F (2011-05-25)

This research addresses the gap in characterizing the climate structure in the eastern United States for suitability of winegrape growth. Even though all of the lower 48 contiguous states grow winegrapes and produce wine, ...
The Impact of ENSO on the Extratropics

Jin, Daeho (2008-07-11)

The impact of tropical remote forcing on the extratropics is examined with ideal El Niño-Southern Oscillation (ENSO) forcing in the tropical Pacific. A set of numerical experiments are described in which perfectly periodic ...
The Impact of the Global Tiger Recovery Program on Wildlife Crime

Balajapalli, Sudha (2015-10-12)

At the end of the 19th century, there were 100,000 wild tigers (Wikramanayake et al., 2011). Today, there are 3,200-3,600 wild tigers (Seidensticker, 2010). Next to habitat destruction, wildlife crime is the second-largest ...
Implementation of a Hydrological Model Based on Full Resolution 3D LIDAR Point Clouds

Gallagher, Andrew J. (2013-02-12)

The work presented here describes the design and implementation of a hydrological model based on high resolution 3D LIDAR data sets. The model incorporates existing hydrological concepts combined with novel computational ...
Implementation of Meaningful Watershed Education Experiences (MWEE’s) by Middle School Life Science Teachers

Kinne, Lauren Walsh (2014-04-02)

As anthropogenic stressors impact local ecosystems, fostering environmentally responsible behaviors in our students continues to be relevant and important. This study examined the impact of teachers’ education, training ...

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